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Notebook

Antithrombotics in vascular disease and renal dysfunction

Journal of the American College of Cardiology

This analysis evaluated whether the benefits of rivaroxaban 2.5 mg bd plus aspirin, comparedwith aspirin alone, are maintained in vascular patients who also have renal dysfunction.

Notebook

Fracassi F, Crea F, et al.

Volume 73, Issue 18, May 2019

This study examined the prevalence,morphological features, and significance ofhealed plaques at the culprit site in patients withacute coronary syndromes usingoptical coherence tomography.

Notebook

White blood cells and Blood Pressure

Current understanding of blood pressure regulation involves role of autonomic nervous system, vasculature and renal function. Emerging experimental data suggests role of immune system in regulation of blood pressure. Thus it becomes important to evaluate the role of immune system in development of hypertension. Mendelian randomization analysis helps to understand relation of genetic mutations with particular disease.

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Notebook

Left Atrial Appendage Closure Versus Direct Oral Anticoagulants in High-Risk Patients with Atrial Fi...

Stroke prevention in patients with atrial fibrillation (AF) is an important aspect of management of AF. Percutaneous Left Atrial Appendage Closure (LAAC) has been shown to be non-inferior to vitamin K antagonists for stroke prevention. Availability of Direct oral anticoagulants (DOACs) has improved the safety of oral anticoagulation with less bleeding as compared to VKAs.

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